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⇕ Free Read Format Kindle ぎ The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms eBook: Michael S. Wolfe: Amazon.fr: Amazon Media EU S.à r.l. ⥹ By Michael S Wolfe ⧭ The Molecular and Cellular Basis of Neurodegenerative Diseases Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimers, Parkinsons, frontotemporal dementia, ALS, Huntingtons, and prion diseases Edited and authored by internationally recognized leaders in the field, the book s chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics Diseases are presented first, with common mechanisms later Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.Covers the spectrum of neurodegenerative diseases and their complex genetic, pathological, biochemical and cellular featuresFocuses on leading hypotheses regarding the biochemical and cellular dysfunctions that cause neurodegenerationDetails features, advantages and limitations of animal models, as well as prospects for therapeutic developmentAuthored by internationally recognized leaders in the fieldIncludes illustrations that help clarify and consolidate complex conceptsMichael S Wolfe is the Mathias P Mertes Professor of Medicinal Chemistry at the University of Kansas He received his B.S in chemistry in 1984 from the Philadelphia College of Pharmacy and Science and Ph.D in medicinal chemistry in 1990 from the University of Kansas After postdoctoral stints at the University of Kansas medicinal chemistry and the NIH cell biology , he joined the faculty of the University of Tennessee in Memphis in 1994 In 1999, he joined the faculty at Brigham and Womens Hospital and Harvard Medical School in Boston, becoming Professor of Neurology in 2008 Prof Wolfes work has focused on understanding the molecular basis of Alzheimers disease and related disorders, and identifying effective approaches for pharmacological intervention Awards for his work include the Sato Memorial International Award in bioorganic and medicinal chemistry from the Pharmaceutical Society of Japan 2003 , the MetLife Award for Biomedical Research 2008 , a Zenith Fellows Award from the Alzheimers Association 2008 , and the Potamkin Prize from the American Academy of Neurology 2009. 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Wolfe: Amazon.fr: Amazon Media EU S.à r.l.